Basic Info.
Model NO.
Frazer-Acetaminophen
Certification
GMP, HSE, ISO 9001, USP, BP
Suitable for
Elderly, Children, Adult
Purity
>99%
Assay
90% Min Paracetamol
Test
HPLC
Storage
Cool Dry Place
MW
240.75
Grade Standard
Medicine Grade
Shelf Life
2 Years Proper Storage
Active Ingredient
Paracetamol
Case No
103-90-2
Sample
Paracetamol Avaliable
Package
1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
Appearance
White Powder
Color
White
Certificate
GMP ISO USP Bp
Transport Package
Foil Bag
Specification
99%
Trademark
Xi′an Frazer Biotech Co., Ltd.
Origin
China
Production Capacity
1000kg/Month
Product Description
Factory Supply High Quality Acetaminophen CAS#103-90-2


Basic detials:
Product Name | Paracetamol bp |
Appearance | White or white crystalline powder |
Assay | 99%min |
Test | HPLC |
Certificate | ISO 9001 |
CAS | 103-90-2 |
MF | C17H19N3O3S |
Einecs No | 137-58-6 |
Dosage Form | Powder |
Storage Temperature | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |
Shelf Life | 24 Months |
What is Paracetamol?
Paracetamol:
Mainly used for amino acid infusion,due to special wettability, also used in cold cream,osmetics. Serine constitute the human body of several kinds of essential amino acid of protein a, for the construction of protein has a very important role.
The antipyretic and analgesic acetaminophen, this product is a metabolite of , regulates central prostaglandin synthase by inhibiting hypothalamic body temperature. Reduce the synthesis and release of prostaglandin PGE1, bradykinin and histamine. PGE1 mainly acts on the nerve center.
Purpose:
1. Paracetamol is the most commonly used non-inflammatory antipyretic analgesic. Its antipyretic effect is similar, its analgesic effect is weak, and it has no anti-inflammatory and anti rheumatic effect.
2. Paracetamol is used as antipyretic, analgesic and anti rheumatic drugs
3. Paracetamol is used in organic synthesis intermediates, photographic chemicals and non anti-inflammatory, antipyretic and analgesic drugs.
Usage Method:
1. Oral administration of
(1) paracetamol tablets and capsules: 300 ~ 600mg for adults once, 3 ~ 4 times a day as required, and the daily dosage should not be > 2G. Antipyretic treatment generally does not exceed 3 days, and analgesic administration does not exceed 10 days. Children take 10 ~ 15mg / kg once every 4 ~ 6h; The dose of small chemicalbook infants under 12 years old shall not exceed 5 times a day, and the course of treatment shall not exceed 5 days. This product is not suitable for long-term use.
2. Dispersible tablets: when taking, heat boiled water to disperse. The commonly used dose for children is 10 ~ 15mg / kg once, once every 4 ~ 6h. The dose for children under 12 years old shall not exceed 5 times a day, and the course of treatment shall not exceed 5 days. The dose for children under 3 years old shall be reduced as appropriate.
COA
Tests | Standards | Results |
Appearance | White or almost white ,crystalline powder. | White,crystalline powder. |
Identification | A:IR absorption | Complies |
B:UV absorption | Complies | |
C:TLC | Complies | |
Melting point | 168~172°C | 169.0~170.9°C |
Water | Not more than0.5% | 0.08% |
Related substance | ImpurityJ(chloroacetanilide)not more than 10 ppm | 2ppm |
Impurity K(4-aminophenolly)not more than 50 ppm | 15 ppm | |
Impurity F(4-nitrophenolly)not more than 0.05% | Not detected | |
any other impurity not more than 0.05% | 0.01% | |
Total of other impurities not more than 0.1% | 0.02% | |
Residue on ignition | Not more than 0.1% | 0.05% |
Chloride | Not more than 0.014% | Less than 0.014% |
Sulfate | Not more than 0.02% | Less than 0.02% |
Sulfide | Conforms | Conforms |
Heavy metals | Not more than 0.001% | Less than 0.001% |
Free p-aminophenol | Not more than 0.005% | Less than 0.005% |
Limit of P-chloroacetanilide | Not more than 0.001% | Less than 0.001% |
Readily carbonizable substances | Conforms | Conforms |
Residual solvents | Residual content of acetic acid is limited by the test of loss on dryingnot more than0.5% | 0.08% |
Assay(anhydrous basis) | 99.0~101.0% | 99.6% |
Conclusion: Complies with USP34/ BP2011 |
